| abstract |
[Chemical 1] The compounds of formula I are HIV reverse transcriptase inhibitors, where V, W, X, Y, Z, R 1 , R 2 , R 4 , R 5 , R 6 , ring A, ring B, j , And k are defined herein. Compounds of formula I, and pharmaceutically acceptable salts and prodrugs thereof, are useful in the inhibition of HIV reverse transcriptase, prevention and treatment of infection by HIV, and prevention, delay of onset or progression of AIDS, and treatment It is. The compounds and salts thereof may be used as components in pharmaceutical compositions, optionally in combination with other antiviral agents, immunomodulators, antibodies, or vaccines. |