| abstract |
The present invention relates to amyloidosis (amyloidosis), diseases and disorders associated with amyloid plaque formation by increasing tissue endogenous macrophage activity in an organ or tissue of an animal that requires treatment by systemic administration of a colony stimulating factor. For example, to a method of treating Alzheimer's disease. For example, the activity of bone marrow-derived microglial cells in an organ or tissue can be determined by either colony stimulating factors, particularly macrophage colony stimulating factor, either alone or in combination with additional colony stimulating factors, stem cell factors or other compounds that can treat amyloidosis. Can be increased by systemic administration. |