| abstract |
The present invention relates to binding molecules capable of binding to rat, cynomolgus monkey and human LINGO polypeptides, polynucleotides encoding such binding molecules; expression vectors comprising said polynucleotides; expression comprising polynucleotides capable of generating binding molecules A system; an isolated host cell comprising an expression system as defined above; the use of such a binding molecule as a pharmaceutical, particularly in a treatment to promote axonal regeneration / plasticity; a pharmaceutical composition comprising said binding molecule And methods of treatment of diseases associated with axonal degeneration and demyelination. |