abstract |
The present invention relates to compositions and methods related to Toll-like receptor (TLR) polypeptides. In some embodiments, the present invention relates to managing TLR3-related diseases. In a further aspect, the present invention relates to a method for preventing and treating inflammation. In some embodiments, the present invention relates to TLR3 antagonists, amino acid sequences that act as dominant negative molecules, and nucleic acid sequences that encode the amino acid sequences. In additional embodiments, the present invention relates to the manipulation of biological material to assess TLR3 activity. |