http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010508499-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-56 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-416 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-37 |
| filingDate | 2007-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2010-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2010508499-A |
| titleOfInvention | Method and apparatus for electrochemical measurement of factor XA inhibitors in blood samples |
| abstract | The present invention relates to a method and apparatus for measuring factor Xa inhibitors in blood samples, in particular heparin and fractionated heparin or low molecular weight heparin and direct factor Xa inhibitors, wherein the blood sample can be cleaved by thrombin. A detection reagent comprising at least one thrombin substrate consisting of a peptide residue amide-bonded to an electrogenic substance via the carboxyl terminus, and conversion of known amounts of Factor X reagent and Factor X to Factor Xa The first step of contacting with the activator reagent to induce, the amount or activity of the electrogenic substance cleaved from the thrombin substrate by factor Xa-mediated thrombin activation and / or its time course using electrochemical methods Second step of measuring as a measured signal, and finally factor Xa in the blood sample to be analyzed It is characterized by a third step in which the amount of inhibitor or the corresponding measured amount, in particular the corresponding clotting time, is measured on the basis of this measurement signal. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012124800-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2017130528-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7009998-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-5946139-B2 |
| priorityDate | 2006-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 82.