http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010507639-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D475-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D475-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 |
| filingDate | 2007-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2010-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2010507639-A |
| titleOfInvention | Pteridine derivatives as polo-like kinase inhibitors useful in the treatment of cancer |
| abstract | The compounds of formula (I) are inhibitors of polo-like kinases (PLKs) and are useful in the treatment of cell proliferative diseases: [Wherein R 1 and R 2 are hydrogen, or (C 1 -C 6 ) alkyl, (C 2 -C 6 ) alkenyl, (C 2 -C 6 ) alkynyl or (C 3 -C 6 ) cycloalkyl groups; R 3 and R 3 ′ are independently hydrogen, —CN, hydroxy, halogen, optionally substituted (C 1 -C 6 ) alkyl, (C 2 -C 6 ) alkenyl, (C 2 -C 6 ) alkynyl or (C 3 -C 6 ) cycloalkyl, —NR 5 R 6, where R 5 and R 6 are independently hydrogen or optionally substituted Optionally selected (C 1 -C 6 ) alkyl) or C 1 -C 4 alkoxy; ring A is an optionally substituted monocyclic or bicyclic carbocycle or heterocycle Is a ring or a ring system having up to 12 ring atoms; T is connected to ring A by a linker RL 1 -Y 1- as defined in the claim, RL 1 -Y 1- (Where R is an α amino acid or Is a group of α amino acid ester groups] [Selection figure] None |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2022504601-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7130123-B2 |
| priorityDate | 2006-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 428.