abstract |
The present invention provides a Micrococcineae spp protease that has undergone multiple substitutions. In particular, the present invention relates to serine proteases having a plurality of substitutions, DNAs encoding these proteases, vectors containing DNAs encoding these proteases, host cells transformed with this vector DNA, this host An enzyme produced by a cell is provided. The present invention also provides a detergent composition (eg, detergent composition), animal feed composition, fiber and leather treatment composition comprising these serine protease variants. In particular, in a preferred embodiment, the present invention provides mutant (ie, mutated) proteases derived from the wild-type proteases described herein. These mutant proteases also have many uses. |