| abstract |
Represents an optional double bond, the dotted line is a double bond or a single bond allowed by the valence requirement, optionally a bond or no bond, E, A, G, M, Het, B, A heterocyclic of formula (I), wherein X, R 3 , R 10 , R 11 , R 32 and R 33 are as defined herein, and the remaining substituents are as defined herein. Substituted tricycles or pharmaceutically acceptable salts or solvates, isomers or racemic mixtures of the compounds, and pharmaceutical compositions containing them, and thrombosis, atherosclerosis, restenosis by administering the compounds Disclosed are methods for treating diseases associated with hypertension, angina, arrhythmias, heart failure and cancer. Claim for combination therapy with other cardiovascular drugs. |