abstract |
The present invention act primarily as a glucose-dependent insulin secretagogue, formula (I): AZ 1 -Z 2 -Z 3 -Z 4 -Z 5 -Z 6 -Z 7 -Z 8 -Z 9 - A novel peptidomimetic of Z 10 -Z 11 -B is provided. Furthermore, these peptidomimetics were found to exhibit glucagon receptor antagonist activity along with GLP-1 receptor agonist activity. |