abstract |
The present invention relates to IL-17 receptor A (IL-17RA or IL-17R) antigen binding proteins, such as antibodies, polynucleotide sequences encoding the antigen binding protein, and IL-17 reception by one or more IL-17 ligands. The present invention relates to compositions and methods for diagnosing and treating diseases mediated by body A activation. The present invention relates to the identification of neutralizing determinants on IL-17 receptor A (IL-17RA or IL-17R) and antibodies that bind to it. Aspects of the invention also include antibodies that compete with the IL-17RA neutralizing antibodies described herein for binding. [Selection] Figure 10 |