| abstract |
The present invention relates to novel glutaminyl-peptide cyclotransferase-like proteins (QPCTL), which are isozymes of glutaminyl cyclase (QC, EC 2.3.2.5), and isolated nucleic acids encoding these isozymes, all of which are It is useful for the discovery of new therapeutic agents, for measuring cyclase activity, and for determining the inhibitory activity of compounds against these glutaminyl cyclase isozymes. [Selection figure] None |