| abstract |
Treatment of chronic pain, particularly inflammatory pain and neuropathic pain, is an important area where medical needs are not yet met. Disclosed are compounds of formula (I) and compounds of formula (IIA), wherein R 1 , R 2 , R 3 , R 4 , R 5 , u and v are as defined herein. . These compounds can be used in methods of treating pain (eg, inflammatory pain, chronic pain, and neuropathic pain), methods of treating diabetes, and methods of inhibiting cholesterol absorption. |