| abstract |
A compound of formula (I) wherein Z 1 is βCH 2 β or βC (O) β, R 4 and R 5 are carbon chains (optionally both C 2 bridged , U and v are independently an integer from 0 to 3 such that the sum is 3 to 5, R 2 is heteroaryl, and R 1 and R 3 are as defined herein. Disclosed are compounds as defined. Also disclosed are methods of treating pain using compounds of formula (I). Another embodiment of the invention is an effective amount of at least one (eg, one) compound of formula I, an effective amount of at least one (eg, one) other pharmaceutically active ingredients (ie, , An agent) (eg, at least one other agent for the treatment of pain such as inflammatory pain, chronic pain, or neuropathic pain), and a pharmaceutically acceptable carrier. |