| abstract |
Immunostimulatory single-stranded oligoribonucleotides (ssORN) with a phosphodiester backbone induce TLR7-independent and MyD88-dependent immune activation. These immunostimulatory ssORNs elicit a Th1-like immune response in the subject, elicit an antigen-specific immune response in the subject, and treat subjects with cancer, infections, allergic conditions, or asthma Useful for. [Figure 1] |