abstract |
The present invention is a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of a SCAP gene (human SCAP gene), which is less than 30 nucleotides in length, generally 19 to 25 nucleotides in length, and at least the SCAP gene It relates to a dsRNA comprising an antisense strand having a partially complementary nucleotide sequence. The present invention relates to a pharmaceutical composition comprising dsRNA together with a pharmaceutically acceptable carrier; a method of treating diseases caused by human SCAP expression and SCAP gene expression using the pharmaceutical composition; and It also relates to a method of inhibiting expression. |