| abstract |
Provided is a crosslinked derivative of polycarboxylated polysaccharide comprising hyaluronic acid or a derivative thereof. A cross-linked derivative of a polycarboxylated polysaccharide comprising hyaluronic acid or a derivative thereof cross-linked by “click chemistry” type reaction at least one of the polysaccharide chains is used. It describes its use as a matrix in the field of intra-articular replacement therapy, plastic surgery, tumor reconstruction surgery and also for the controlled release system of biologically and / or pharmacologically active molecules and / or macromolecules. [Selection] Figure 3 |