| abstract |
An antibacterial compound is provided. Antimicrobial compounds of formula (I) are provided: as well as their stereoisomers, pharmaceutically acceptable salts, esters and prodrugs; pharmaceutical compositions containing such compounds Methods of treating bacterial infections by administering such compounds; and methods of preparing the compounds are provided. The present invention relates to novel compounds, pharmaceutical compositions containing the compounds, methods for inhibiting UDP-3-O- (R-3-hydroxydecanoyl) -N-acetylglucosamine deacetylase (LpxC), and grams Methods of treating negative bacterial infections are provided. [Selection figure] None |