| abstract |
[PROBLEMS] To treat chronic pain. The present invention activates an analgesic α-adrenergic receptor in a subject in the absence of α-2A receptor activation for a period of at least 3 days, resulting in the relief of chronic pain. Provided is a method for alleviating chronic pain in a subject over time by being maintained in the absence of continued activation of the receptor. The analgesic α-adrenergic receptor can be, for example, an α-2B receptor. [Selection] Figure 1 |