| abstract |
An anti-inflammatory composition comprising docosahexaenoyl lysophosphatidylamine as an active ingredient is provided. SOLUTION: Docosahexaenoyl lysophosphatidylcholine, which is a polyunsaturated lysophosphatidylcholine, suppresses the formation of lipid polysaccharide-derived NO in cells and inhibits zymosan A-induced peritonitis in vivo. Since it has excellent anti-inflammatory efficacy and almost no cytotoxicity, it can be usefully used as a pharmaceutical composition for preventing and treating inflammatory diseases, or as an active ingredient of health foods. [Selection figure] None |