| abstract |
A novel method for producing 1,3-dioxane-2-alkylcarbamate having pharmacological activity is provided. SOLUTION: General formula (I) [Wherein R 1 is a phenyl group which may be substituted with one or more halogen atoms or hydroxy, etc .; R 2 is a general formula CHR 3 CONHR 4 (where R 3 represents a hydrogen atom or a methyl group; R 4 represents a hydrogen atom or a group such as (C 1 -C 3 ) alkyl, (C 3 -C 5 ) cycloalkyl or (pyridin-4-yl) methyl group), and n is 1 to A method for producing 1,3-dioxane-2-alkylcarbamate represented by the formula [3] by reacting 1,3-dioxane-2-alkylamines with a phenyl carbonate derivative. [Selection figure] None |