| abstract |
Disclosed is a compound useful for the treatment of neurological diseases related to the production of amyloid β protein and neurological diseases such as Alzheimer's disease. Formula (I) [Wherein X is CH2, O, NR1, SO2 or S] N2-[(3,5-difluorophenyl) acetyl] -N1-[(2R, 3R) -2- (2,5-difluorophenyl) -4-oxo-2,3, having the structure represented by A compound that inhibits γ-secretase activity represented by 4,5-tetrahydro-1,5-benzothiazepin-3-yl] -L-alaninamide. [Selection figure] None |