http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010229044-A

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-107
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-13
filingDate 2009-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_baf812ed6642d5aaed8a6b10006d2c73
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af4458ab8a39cf4190781329d9bcb363
publicationDate 2010-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2010229044-A
titleOfInvention Methods for modifying proteins
abstract The present invention provides a protein modification method capable of maintaining the activity of two or more specific binding sites of a protein. A method of modifying a protein having a first specific binding site 21 and a second specific binding site 22 with a modifying substance, wherein the first specific binding site 21 specifically binds to the first specific binding site 21. A first step in which a protein 2 is brought into contact with one protective agent 1, a second step in which a modifying substance 3 is supplied to the protein 2, a first step in which the first protective agent 1 and the first specific binding site 21 are dissociated. 3 steps, the second protective agent 4 that specifically binds to the second specific binding site 22 is brought into contact with the protein 2 that has passed through the first to third steps in order, and the second specific binding by the modifier 3 A method comprising a fourth step of removing the protein 2 in which the site 22 is inactivated, and a fifth step of dissociating the second protective agent 4 and the second specific binding site 22. [Selection] Figure 1
priorityDate 2009-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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