abstract |
PROBLEM TO BE SOLVED: To provide a method capable of producing 7,8-difluoro-2-naphthol from 2,3-difluorophenylacetic acid as a raw material with a simpler operation and at a lower cost. A step of converting 2,3-difluorophenylacetic acid into an acid halide with a halogenating agent and reacting with ethylene in the presence of a Lewis acid to obtain 7,8-difluoro-2-tetralone, 7,8-difluoro A process for producing 7,8-difluoro-2-naphthol comprising a step of purifying 2-tetralone to 2-acetoxy-7,8-difluoronaphthalene with acid anhydride and sulfuric acid, and a step of deacetylating this . [Selection figure] None |