abstract |
Muscle spasms such as excessive urination, diarrhea, increased urine output, withdrawal syndrome, pain such as neuropathic pain, neurodegenerative diseases, memory and cognitive deficits, psychosis such as mania, anxiety, hypertension, cardiac ischemia, Treat congestive heart failure and nasal congestion without sedation or cardiovascular side effects. A compound having selective agonist activity at one or both of an α2B and α2C adrenergic receptor subtype as compared to an α2A adrenergic receptor subtype is used as a therapeutic agent. The active compound is selected from the group of compounds of formula I below and defined in the specification: [Selection figure] None |