| abstract |
An immediate release pharmaceutical formulation useful for the treatment of cardiovascular disorders comprising a pharmaceutically acceptable diluent or carrier. Formula (I) as an active ingredient: Wherein R 1 represents C 1-2 alkyl substituted with one or more fluoro substituents, R 2 represents hydrogen, hydroxy, methoxy or ethoxy, and n represents 0, 1 or 2. To express. Or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable diluent or carrier. However, when the active ingredient is other than in the salt form, the formulation comprises one active ingredient and water solution, one active ingredient and dimethyl sulfoxide solution, and 5: 5: 90 ethanol: PEG660 12-hydroxy. Stearate: does not contain alone a solution of one active ingredient in a mixture of water. [Selection figure] None |