abstract |
The present invention provides a substrate for blood-compatible coating of a surface, a method for coating the same, and a method for using them on a surface to prevent or reduce unwanted reactions. The use of oligosaccharides and polysaccharides, including the sugar units N-acylglucosamine or N-acylgalactosamine, and the use of these oligosaccharides and / or polysaccharides to tune selected blood compatible surfaces And a method for blood compatible coating of surfaces with said oligosaccharides and / or polysaccharides, modeled on common biosynthetic precursor materials of heparin, heparan sulfate and chitosan. Furthermore, it relates to a method for producing said oligosaccharides and / or polysaccharides and various uses of blood compatible coated surfaces. More particularly, the use of said oligosaccharides and / or polysaccharides in a stent to which a blood compatible coating comprising an antiproliferative, anti-inflammatory and / or antithrombotic active substance is attached. [Selection] Figure 1 |