| abstract |
A crystalline polymorphic form of a bisulfate salt of a thrombin receptor antagonist is provided. According to the process shown in the following formula, compound 2 which is a crystalline polymorphic form of hydrogen sulfate is obtained from thrombin receptor antagonist compound 1. Compound 2 is more stable than Compound 1. The compound is thrombosis, atherosclerosis, restenosis, hypertension, angina, arrhythmia, heart failure, myocardial infarction, glomerulonephritis, thrombotic stroke, thromboembolic stroke, peripheral vascular disease, inflammatory It can be used in a pharmaceutical composition for treating a disorder, cerebral ischemia, or cancer. [Selection figure] None |