| abstract |
A compound having calpain inhibitory activity is provided. The following general formula (I) [Wherein, R 1 represents a lower alkyl group, R 2 represents hydrogen, halogen, cyano group, lower alkyl group or lower alkoxy group, and n represents 0 or 1. ] The compound represented by this. In particular, (2S) -4-methyl-2-(((phenylamino) thioxomethyl) amino) -N-((3S) -tetrahydro-2-hydroxy-3-furanyl) pentanamide. This compound is useful as a preventive or therapeutic agent for diseases involving calpain. [Selection figure] None |