abstract |
PROBLEM TO BE SOLVED: To provide a vaccine for human preventive or therapeutic immunity against HIV. [Solution] The invention relates to the manufacture of a vaccine suitable for priming-boost delivery for human prophylactic or therapeutic immunity against HIV, a) an HIV Tat protein or polynucleotide; or b) an HIV Nef protein or polynucleotide; or c) an HIV Tat protein or polynucleotide bound to an HIV Nef protein or polynucleotide; And HIV gp120 protein or polynucleotide, Wherein the protein or polynucleotide is delivered by a bombardment technique. [Selection figure] None |