| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3e76762cb56a1163ea731289dfca9e00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-197
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 |
| filingDate |
2009-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56b2960228404e29b50fda533e671546
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da95c2dc1cd2c198f4fa7a73dfad1c7b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a588c70ae6e794824e881488e7a30965
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1464085f7b62f960f24297cf36abbdf5 |
| publicationDate |
2010-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2010180145-A |
| titleOfInvention |
Method for producing tranexamic acid-containing nanoparticles and composite particles |
| abstract |
Disclosed are a tranexamic acid-containing nanoparticle having a high skin permeability average particle diameter of less than 100 nm, and a simple and low-cost production method of a composite particle obtained by combining the nanoparticle. An aqueous solution in which tranexamic acid is dissolved and a solution in which a biocompatible polymer is mixed with an organic solvent are mixed, and the suspension of tranexamic acid-containing nanoparticles in which tranexamic acid is encapsulated in the biocompatible polymer is provided. Use a suspension. Next, the organic solvent is distilled off from the suspension of tranexamic acid-containing nanoparticles. Thereby, tranexamic acid-containing nanoparticles having high skin permeability suitable as a raw material for cosmetics and external medicines can be produced. [Selection figure] None |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-5959728-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10011681-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7222236-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7222232-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014168134-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2017066095-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2019172655-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2019172654-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10258694-B2 |
| priorityDate |
2009-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |