| abstract |
The purpose of the present invention is to elucidate the function and molecular basis of Tex19, particularly the function in spermatogonial stem cells, and to contribute to the use in various fields. A method for determining or detecting pluripotency or differentiation ability in a stem cell based on variation in the expression level of the Tex19 gene in a stem cell, a detection marker for spermatogenic ability in a spermatogonial stem cell, comprising an expression product of the Tex19 gene A Tex19 knockout animal exhibiting male sterility, a method for screening a substance for treating male sterility using the Tex19 knockout animal, a stem cell line in which Tex19 is disrupted, and the like. [Selection] Figure 2 |