| abstract |
The present invention provides a novel benzoazepine compound having excellent properties such as the ability to maintain a tolvaptan blood concentration capable of exhibiting a desired medicinal effect over a long period of time. The following equation (1) [Wherein R 1 represents a group —CO— (CH 2 ) n —COR 2 or the like. n represents an integer of 1 to 4, R 2 represents a hydroxyl group; a lower alkoxy which may have a hydroxyl group, a lower alkanoyl group, a lower alkanoyloxy group, a lower alkoxycarbonyloxy group, a cycloalkyloxycarbonyloxy group or the like as a substituent. Group; or a specific amino group. ] [Selection figure] None |