| abstract |
Provided are a library, a vector, a phage particle, a host cell, and a method for displaying a Kunitz domain. A library comprising a plurality of filamentous phage particles, wherein each phage particle is sufficient to produce (i) a display protein comprising a Kunitz domain, (ii) (a) an infectious phage particle. A nucleic acid comprising a phage gene and (b) a sequence encoding a display protein, wherein the Kunitz domain comprises at least one diverse amino acid position in each of the two interaction loops, A library where the positions are varied among multiple particles and the average number of copies of the Kunitz domain per phage particle is less than 2.0. [Selection figure] None |