http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010160018-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_58ff2756c7b40c7e2865d08134a14c6f |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 |
| filingDate | 2009-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec99ce63856fd659e82fc82301ab31a8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ef3800b5b606f6729a855151c627edc8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a33576d819df43101528e2a959005dc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98ce0dbb317d0c7209de09aa621d5575 |
| publicationDate | 2010-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2010160018-A |
| titleOfInvention | Cell analysis method using immunohistochemical staining |
| abstract | Programmed cell death, cancer cells, and tissue stem cells are discriminated in a pathological tissue specimen section so as to be sufficiently examined. An anti-apoptotic factor comprising cleaved caspase-3, which indicates the onset of irreversible apoptosis, and survivin, which appears to be cancer cells, in human formalin-fixed paraffin-embedded pathological tissue specimens using antibodies or antibody panels Bcl-2, Flip, AATF, etc.), beclin-1 involved in autophagic vacuolar nucleus formation, LC3 involved in vacuolation, and specific antigens of mitochondria and lysosomes were subjected to antigen recovery immunostaining and It was possible to identify malignant tumor cells and tissue stem cells by the status of cell death and survivin. These means that new information can be added to the pathological diagnosis, and the therapeutic effect and the like can be evaluated by pathological specimen analysis before and after antitumor treatment or the like. [Selection] Figure 1 |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111471111-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111471111-B |
| priorityDate | 2009-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 298.