| abstract |
The present invention provides biocompatible hyaluronic acid-supporting nanoparticles and hyaluronic acid-containing composite particles that have both a hyaluronic acid penetration effect and a sustained-release effect into the skin, and a cosmetic with a high moisturizing effect using them. A hyaluronic acid-carrying nanoparticle 1 includes hyaluronic acid 4a encapsulated in a nanoparticle formed of a biocompatible polymer 2. Further, the nanoparticle surface is coated with the cationic polymer 5 and the hyaluronic acid 4b is electrostatically supported. [Selection] Figure 2 |