| abstract |
Biologically active peptides and polypeptides that can be used as therapeutic or prophylactic agents for diseases or disorders associated with NGF (nerve growth factor) as a causative factor. A novel binding agent or NGF-binding peptide to NGF, which is useful for regulating NGF activity and managing pain. A pharmacologically active modified polypeptide comprising the above peptide linked to one or more Fc domains. And a method of treating or preventing a disease or disorder associated with NGF activity, comprising administering a therapeutically effective amount of a composition containing the modified polypeptide. [Selection figure] None |