| abstract |
An effective dosing regimen, kit and use thereof for neural stem cell proliferating agents and neural stem cell differentiating agents. The present invention provides an effective dosing regimen for a neural stem cell proliferating agent, a kit comprising an effective dosing regimen for a neural stem cell proliferating agent, and uses thereof. In particular, in contrast to high dose administration in the short term, neural stem cell proliferating agents are delivered continuously to mammalian subjects at low doses. In particular, the present invention provides a kit for providing an effective amount of a neural stem cell proliferating agent, comprising: (a) a dose of the neural stem cell proliferating agent administered continuously during a first treatment period, wherein the first A dose wherein the total dose of neural stem cell proliferating agent administered during the treatment period is equal to an amount effective to treat or ameliorate a neurodegenerative disease in a mammal, and wherein the first treatment period is at least 3 days; (b) Instructions for using the kit are provided. [Selection] Figure 1 |