| abstract |
PROBLEM TO BE SOLVED: To provide a liposome useful in a method for administering an active substance using mild hyperthermia conditions. A liposome comprising an active substance, comprising a lipid bilayer membrane comprising phospholipid and lysolipid, wherein phospholipid is a primary lipid source of the lipid bilayer membrane and the lysolipid is not present The lysolipid is included in the bilayer membrane in an amount sufficient to increase the percentage of active agent released at the phase transition temperature compared to what occurs. [Selection] Figure 1 |