| abstract |
Disclosed is a liquid formulation ready for use with a botulinum toxin that can be conveniently transported, stored, and used. A composition for treating a patient in need of inhibiting cholinergic input to selected muscles, muscle groups, glands or organs. A stable liquid pharmaceutical botulinum toxin formulation ready for use in a pharmaceutically effective dose comprising: (a) a phosphate buffer, a phosphate-citrate buffer, and succinic acid A pharmaceutically acceptable buffered saline solution comprising a buffer component selected from the group consisting of a buffer; (b) serum albumin; and (c) an isolated botulinum toxin; Stable as a liquid for at least 1 year at a temperature between 10 ° C. and 10 ° C. ± 10%, or as a liquid for at least 6 months at a temperature between 10 ° C. and 30 ° C. ± 10% Yes, the composition is suitable for pharmaceutical administration to a mammal without the need for further reconstitution. [Selection figure] None |