http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010136691-A

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filingDate 2008-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb6ab2b81a28c7ae49142ed1bedba878
publicationDate 2010-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2010136691-A
titleOfInvention Method and apparatus for detecting chromosomal structural abnormalities
abstract In a method for detecting a gene translocation having an abnormal chromosome structure, a mixture of a plurality of nucleic acid probes, a probe that crosses a predetermined breakpoint region, A first probe straddling the cut point from upstream of the cut point; A method for detecting a structural abnormality of a chromosome, characterized in that a second probe from the downstream of a breakpoint before or before the breakpoint is labeled with a different label. [Effects] When detecting a structural abnormality of a chromosome by combining a probe labeled with a nucleic acid or a nucleic acid analog with a complementary chromosomal region, the frequency of false positives decreases, and even a fine structural abnormality can be detected. . [Selection] Figure 2
priorityDate 2008-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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