http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010133720-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cdd94f212dc7aef02fc1dcf28fa9b4fd |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-544 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-78 |
| filingDate | 2008-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_82083b887adc50188de341cc791224e8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9eb09e797e7024292ebddd5f8fc28572 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_80cdecd63fc94b8bffde0c80fe8eca65 |
| publicationDate | 2010-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2010133720-A |
| titleOfInvention | Method and system for predicting pharmacokinetics of fine particle formulation |
| abstract | A method for predicting the pharmacokinetics of a fine particle formulation from in vitro results, a system for carrying out the method, a selection method using the method, and a correlation between results obtained in vitro and in vivo A screening kit is provided. A method for predicting the pharmacokinetics of an administered microparticle formulation in vitro, which comprises the following steps (1) and (2). Step (1): Fluorescently labeled microparticle preparation is incubated with two or more kinds of primary cultured cells or cell lines derived from any of liver, blood vessels, blood, lungs and spleen, and flow cytometry is performed over time. The number of cells and the fluorescence intensity thereof are measured, and based on the numerical values measured in step (2): step (1), the absorption ratio or distribution ratio of the preparation for each cell type is predicted. [Selection figure] None |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109893515-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2021043045-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11396017-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109073527-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7271374-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2012012308-A |
| priorityDate | 2008-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 188.