| abstract |
Hyperlipidemia such as hypercholesterolemia, hypertriglyceridemia, hypoHDLemia and / or arteriosclerosis for mammals including humans, showing squalene synthetase inhibitory action and cholesterol synthesis inhibitory action Prophylactic and / or therapeutic drugs. (1) 2-[(4R, 6S) -8-chloro-6- (2-chloro-3-ethoxyphenyl) -1- (trifluoromethyl) -4H, 6H- [1,2, 4] Triazolo [4,3-a] [4,1] benzoxazepin-4-yl] acetic acid (2) 2- (1- {2-[(4R, 6S) -8-chloro-6- (2 -Chloro-3-ethoxyphenyl) -1- (trifluoromethyl) -4H, 6H- [1,2,4] triazolo [4,3-a] [4,1] benzoxazepin-4-yl] acetyl}- A medicament containing a specific compound such as 4-piperidinyl) acetic acid. [Selection figure] None |