| abstract |
Disclosed is a compound for inactivating a pathogen in a substance. Compounds and methods for inactivating pathogens in materials are described, including compositions and methods for inactivation of pathogens in biological materials such as erythrocyte preparations and plasma. The compounds and methods can be used for the treatment of substances intended for in vitro or in vivo use such as clinical trials or blood transfusions. The compound is designed to specifically bind to and react with the nucleic acid and then degrade to form a degradation product. Preferably, the degradation reaction is slower than the reaction with the nucleic acid. [Selection figure] None |