| abstract |
An object of the present invention is to grasp the state of cells in culture and add an additional medium suitable for the state of the cells to produce a target product with an excellent yield. A determination is made based on a culture tank for culturing cells to be cultured, a measurement means for measuring components contained in cultured cells or culture medium cultured in the culture tank, and a measurement value measured by the measurement means. Control means for selecting an additive medium to be added to the culture tank from two or more kinds of additive mediums having different composition ratios based on the state of the cultured cells. [Selection] Figure 1 |