abstract |
A novel class of compounds for the treatment of hyperlipidemia, obesity, and impaired glucose tolerance / non-insulin dependent diabetes mellitus without adversely affecting energy metabolism, and the compounds described above Provision of a pharmaceutical composition for the treatment of obesity, hyperlipidemia, and adult-onset diabetes. A dialkanoic acid compound of formula I, (R1-R4 are each independently H, hydrocarbyl radical; R5 and R6 are each independently H, hydroxyl, lower alkyl, chloro, bromo, cyano, nitro, lower alkoxy, or CF3; Q is linear (CH2) a diradical consisting of n, wherein n is an integer of 2 to 14, and the chain may be optionally substituted with an inert substituent, and their pharmacological properties Acceptable salts, esters, amides and anhydrides. [Selection figure] None |