| abstract |
Disclosed is a compound that is more potent and / or slower to absorb from mucosal surfaces and / or more irreversible than known compounds. The present invention relates to sodium channel blockers. The present invention also includes various treatment methods using these sodium channel blockers. Another aspect of the present invention is to provide compounds that are more potent and / or slower in absorption and / or more irreversible than compounds such as Amilord, Benzamyl, Phenamyl and the like. Accordingly, these compounds have a longer pharmacodynamic half-life than known compounds at the mucosal surface. [Selection] Figure 1 |