| abstract |
Preparation of AT1 receptor antagonist formulations using cyclodextrins, derivatives thereof and / or biodegradable polymers for the treatment of arterial hypertension, other cardiovascular diseases and complications thereof. A far, in the prior art, arterial hypertension, AT1 1 receptor antagonists for the treatment of other cardiovascular diseases and complications thereof, cyclodextrin or derivative and / or a biodegradable polymer No application has been found using. The present invention is a combination of two different techniques, one is a technique of molecularly encapsulating an AT1 1 receptor antagonist in cyclodextrin, and the other is a technique of microencapsulating in a biodegradable polymer. It is characterized by. The present invention also includes an increase and increase of biological effectiveness of the effectiveness of AT1 1 receptor antagonist. The present invention includes a new and more effective alternative for treating arterial hypertension, other cardiovascular diseases and their complications. [Selection figure] None |