| abstract |
The present invention provides a method that can be used in therapeutic angiogenesis by the administration of nicotine or other nicotinic receptor agonists in the treatment of ischemic syndromes such as coronary or peripheral artery disease. Administration of nicotine or other nicotinic receptor agonists that induce angiogenesis to the interior or adjacent regions of ischemic tissue, and substances or prostacyclins that enhance nitric oxide synthesis or activity Administering a substance that enhances the synthesis or activity. [Selection] Figure 6 |