http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010038693-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8fb9f44db08d1c42a53f3d28eaae416f |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-37 |
filingDate | 2008-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7586d1320b05213a3383be8d6c0eb788 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b8a07439400fb47f630756bffe45770d |
publicationDate | 2010-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2010038693-A |
titleOfInvention | Method for evaluating or selecting neutral endopeptidase activity increase inhibitor |
abstract | A method for evaluating or selecting a neutral endopeptidase activity increase inhibitor or a wrinkle inhibitor is provided. The increase in NEP activity in dermal fibroblasts by UVB irradiation was examined. IL-8 and GM-CSF in epidermal cells are involved in NEP activity in dermal fibroblasts. It has been found that the activity of NEP increases as the production amount increases. Then, a substance that inhibits NEP activity and thus suppresses wrinkle formation can be accurately evaluated or selected using the production inhibitory effect of IL-8 and GM-CSF as an index. [Selection figure] None |
priorityDate | 2008-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 683.