| abstract |
Disclosed is a pharmaceutical comprising a compound having an excellent 11β-hydroxysteroid dehydrogenase type 1 inhibitory activity or a pharmacologically acceptable salt thereof as an active ingredient. The general formula (I) [Wherein, R 1 represents a hydrogen atom, a C 1 -C 6 alkyl group, etc .; R 2 represents a C 1 -C 6 alkyl group, a C 1 -C 6 halogenated alkyl group, or a C 1 -C 6 hydroxyalkyl group. R 3 is a hydrogen atom or a C 1 -C 6 alkyl group; R 4 is a compound having a substituted aryl group or a substituted heterocyclic group] or a pharmacologically acceptable salt thereof as an active ingredient. The medicament is effective for the treatment and / or prevention of diabetes, obesity, hyperlipidemia, hypertension or metabolic syndrome. [Selection figure] None |